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PLENHYAGE XL Medium is described in the source material as a 2.0% high-molecular-weight polynucleotide gel supplied in a 2 ml syringe. That concentration distinguishes this record from the Strong variant; product authenticity, allergy history, intended area and individual suitability still require verification.
PLENHYAGE XL Medium is described in the source material as a 2.0% high-molecular-weight polynucleotide gel supplied in a 2 ml syringe. That concentration distinguishes this record from the Strong variant; product authenticity, allergy history, intended area and individual suitability still require verification.
01 / How it works
These chains associate with water to support a hydrated tissue environment. Polynucleotides have been studied for their potential to support fibroblast-related biological activity and extracellular-matrix activity, which may contribute to gradual improvements in texture and elasticity. However, evidence for aesthetic polynucleotide injections is still developing. It is medically inaccurate to guarantee that PLENHYAGE XL Medium will permanently regenerate every damaged cell, create unlimited collagen, or reverse biological ageing.
PLENHYAGE XL Medium is a resorbable injectable gel containing 2.0% high-molecular-weight polynucleotides, equivalent to 20 mg/ml, supplied in a 2 ml syringe. The official manufacturer states that this highly purified material is derived from salmon sperm DNA. Polynucleotides are processed DNA-derived chains; they are not living cells, stem cells, exosomes, or gene therapy, and they do not rewrite your human DNA.
These chains associate with water to support a hydrated tissue environment. Polynucleotides have been studied for their potential to support fibroblast-related biological activity and extracellular-matrix activity, which may contribute to gradual improvements in texture and elasticity. However, evidence for aesthetic polynucleotide injections is still developing. It is medically inaccurate to guarantee that PLENHYAGE XL Medium will permanently regenerate every damaged cell, create unlimited collagen, or reverse biological ageing.
Share the concern, treatment area and change you would like to explore
Shape the approach around your features, preferences and schedule
Experience a carefully planned session with clear guidance throughout
Follow simple aftercare and review how the treatment is progressing

02 / Visual guide
PLENHYAGE XL Medium is a resorbable injectable gel containing 2.0% high-molecular-weight polynucleotides, equivalent to 20 mg/ml, supplied in a 2 ml syringe. The official manufacturer states that this highly purified material is derived from salmon sperm DNA. Polynucleotides are processed DNA-derived chains; they are not living cells, stem cells, exosomes, or gene therapy, and they do not rewrite your human DNA.
Interactive treatment map
Tap a numbered point to move from your concern to the treatment approach, how it works and a personalised plan.

Start with the change you have noticed and the result you would like to explore.
Concerns & areas
Explore common areas and goals, then discuss which are most relevant to you.
Learn how this area can be approached within a personalised treatment plan.
Who may benefit
Treatment Areas: The official manufacturer lists the face, neck, and décolletage as suggested areas. Under-eye use requires strict anatomical assessment and should not be assumed, as it cannot cure all dark circles or dissolve eye bags.
Suitability & Safety: Because the raw material is salmon-derived, patients with a fish or seafood allergy must disclose this before treatment. We will not recommend treatment if you are pregnant, breastfeeding, or have active skin infections. It is not an acne medicine, nor a cure for rosacea or melasma, and cannot erase every scar. Our doctor carefully plans treatments for patients from Mount Austin, Medini, and Singapore, ensuring a safe approach that prioritises diagnosis before product choice.
What to discuss first
03 / Your treatment journey
A calm, well-explained experience at every stage.
Talk through the concern, your previous experiences and the result you would like to explore.
Review the treatment area, suitable options, expected experience and practical timing.
Arrive prepared and receive clear guidance throughout the treatment visit.
Leave with simple aftercare, helpful contact details and a plan for review.
A responsible treatment journey begins with exact-product verification. We check the packaging, confirm the 2.0% concentration in the 2 ml syringe, and ensure the current Malaysian registration covers the exact Medium device.
PLENHYAGE XL Medium is a medical injectable, and minimal downtime does not mean zero downtime. Patients commonly experience temporary redness, swelling, bruising, tenderness, or small raised injection-site bumps that may last longer than 24 to 48 hours. Delayed inflammatory reactions, infections, or nodules are uncommon but possible.
Important Medical Risks: Any facial injection carries a rare risk of accidental vascular compromise. Visual symptoms, blurred vision, or signs of reduced skin blood flow (unusual whitening or grey skin) require immediate medical assessment. There is no guarantee that every complication can be instantly reversed, and hyaluronidase does not dissolve this PN product. We provide detailed aftercare instructions—including avoiding harsh skincare, excessive heat, and unapproved massage—and ensure follow-up is available for all our local and Singapore patients.
04 / Practical expectations
Your experience will reflect the selected treatment, treatment area and individual response. These are the useful details to explore during your visit.
05 / Compare your options
Compare the treatment approach, the area it is designed for, the experience and the way results may develop—not only the name or price.
A useful starting point when you already know the treatment and want to understand it more clearly.
Opens a wider conversation about suitable approaches, timing, recovery and natural-looking results.
Medium contains 2.0% polynucleotides, while Strong contains 2.5%. A higher concentration is not automatically better; the choice depends on the treatment area, tissue condition and clinical goal.
Treatment gallery
Explore the consultation, treatment setting and preparation through a carefully selected visual story.
Related concerns
Begin with the concern you notice, then discover treatment approaches and questions worth bringing to your consultation.
Patient knowledge guide
Four short questions explain the treatment, suitability and why assessment matters. This quiz educates—it does not diagnose or confirm treatment eligibility.
06 / Before you decide
Each treatment has its own considerations. Your consultation is the place to discuss expected benefits, possible side effects, alternatives and anything that may affect timing.
Read about informed consent07 / Recovery
PLENHYAGE XL Medium is a medical injectable, and minimal downtime does not mean zero downtime. Patients commonly experience temporary redness, swelling, bruising, tenderness, or small raised injection-site bumps that may last longer than 24 to 48 hours. Delayed inflammatory reactions, infections, or nodules are uncommon but possible.
Important Medical Risks: Any facial injection carries a rare risk of accidental vascular compromise. Visual symptoms, blurred vision, or signs of reduced skin blood flow (unusual whitening or grey skin) require immediate medical assessment. There is no guarantee that every complication can be instantly reversed, and hyaluronidase does not dissolve this PN product. We provide detailed aftercare instructions—including avoiding harsh skincare, excessive heat, and unapproved massage—and ensure follow-up is available for all our local and Singapore patients.
Contact the clinic08 / FAQ
Helpful answers for planning your consultation and understanding the treatment experience.
A responsible treatment journey begins with exact-product verification. We check the packaging, confirm the 2.0% concentration in the 2 ml syringe, and ensure the current Malaysian registration covers the exact Medium device.
The manufacturer states that the polynucleotide raw material is derived from purified salmon sperm DNA. It is processed biological material, not living salmon cells or gene therapy.
Medium contains 2.0% polynucleotides, while Strong contains 2.5%. A higher concentration is not automatically better; the choice depends on the treatment area, tissue condition and clinical goal.
Under-eye suitability should not be assumed. The exact product instructions, Malaysian registration, anatomy, oedema tendency and cause of the concern must be assessed first.
The product is described as salmon-derived. Anyone with fish, seafood or previous PN-injectable allergy must disclose this and may not be suitable.
Temporary bumps, redness, swelling, bruising, tenderness or itching may occur. Recovery varies by treatment area and individual response.
Plan your next step
Share your goals with the Eco Botanic team and begin with a personalised consultation.