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Plinest NEWGyn® Treatment in Johor Bahru
Plinest NEWGyn® Treatment in Johor Bahru
01 / How it works
At Medi Clinic in Johor Bahru , we prioritise a diagnosis-first approach. Vulvovaginal dryness, burning, or irritation can result from menopause, but similar symptoms may also stem from infection, dermatological conditions, or pelvic-floor dysfunction. Patients from Singapore and Iskandar Malaysia communities like Eco Botanic and Taman Molek trust our doctor-led process because we screen for these causes before recommending treatment. NEWGyn is a non-hormonal option; it is not a vaginal-tightening procedure, structural genital filler, or permanent cure for GSM. A comprehensive medical assessment ensures the treatment aligns safely with your clinical needs.
NEWGyn® is an Italian Class III medical device manufactured by Mastelli S.r.l. specifically developed for selected adult vulvovaginal tissue concerns. Each 2 mL single-use prefilled syringe contains a sterile biorevitalising gel comprising 10 mg/mL of PN-HPT (highly purified polynucleotides), 10 mg/mL of noncrosslinked hyaluronic acid (HA), and 220 micromoles/mL of mannitol. It is intended for selected patients experiencing vulvar or vaginal dryness, reduced tissue hydration, or discomfort associated with confirmed genitourinary syndrome of menopause (GSM).
At Medi Clinic in Johor Bahru , we prioritise a diagnosis-first approach. Vulvovaginal dryness, burning, or irritation can result from menopause, but similar symptoms may also stem from infection, dermatological conditions, or pelvic-floor dysfunction. Patients from Singapore and Iskandar Malaysia communities like Eco Botanic and Taman Molek trust our doctor-led process because we screen for these causes before recommending treatment. NEWGyn is a non-hormonal option; it is not a vaginal-tightening procedure, structural genital filler, or permanent cure for GSM. A comprehensive medical assessment ensures the treatment aligns safely with your clinical needs.
Share the concern, treatment area and change you would like to explore
Shape the approach around your features, preferences and schedule
Experience a carefully planned session with clear guidance throughout
Follow simple aftercare and review how the treatment is progressing

02 / Visual guide
NEWGyn® is an Italian Class III medical device manufactured by Mastelli S.r.l. specifically developed for selected adult vulvovaginal tissue concerns. Each 2 mL single-use prefilled syringe contains a sterile biorevitalising gel comprising 10 mg/mL of PN-HPT (highly purified polynucleotides), 10 mg/mL of noncrosslinked hyaluronic acid (HA), and 220 micromoles/mL of mannitol. It is intended for selected patients experiencing vulvar or vaginal dryness, reduced tissue hydration, or discomfort associated with confirmed genitourinary syndrome of menopause (GSM).
Interactive treatment map
Tap a numbered point to move from your concern to the treatment approach, how it works and a personalised plan.

Start with the change you have noticed and the result you would like to explore.
Concerns & areas
Explore common areas and goals, then discuss which are most relevant to you.
Learn how this area can be approached within a personalised treatment plan.
Learn how this area can be approached within a personalised treatment plan.
Learn how this area can be approached within a personalised treatment plan.
Learn how this area can be approached within a personalised treatment plan.
Who may benefit
Verify GD9561023-122430, current validity, authorised supply, batch and personal exclusions.
What to discuss first
03 / Your treatment journey
A calm, well-explained experience at every stage.
Talk through the concern, your previous experiences and the result you would like to explore.
Review the treatment area, suitable options, expected experience and practical timing.
Arrive prepared and receive clear guidance throughout the treatment visit.
Leave with simple aftercare, helpful contact details and a plan for review.
04 / Practical expectations
Your experience will reflect the selected treatment, treatment area and individual response. These are the useful details to explore during your visit.
05 / Compare your options
Compare the treatment approach, the area it is designed for, the experience and the way results may develop—not only the name or price.
A useful starting point when you already know the treatment and want to understand it more clearly.
Opens a wider conversation about suitable approaches, timing, recovery and natural-looking results.
Treatment gallery
Explore the consultation, treatment setting and preparation through a carefully selected visual story.
Related concerns
Begin with the concern you notice, then discover treatment approaches and questions worth bringing to your consultation.
Patient knowledge guide
Four short questions explain the treatment, suitability and why assessment matters. This quiz educates—it does not diagnose or confirm treatment eligibility.
06 / Before you decide
We believe patients must understand the limits of available clinical evidence. A 2022 pilot study involving 50 postmenopausal women observed improvements in vulvar and vaginal health indices following four sessions. However, this study was small, uncontrolled, and had a short follow-up period. There is no definitive proof that NEWGyn permanently reverses menopause, cures urinary incontinence, or acts identically to vaginal estrogen.
While NEWGyn aims to support tissue hydration and suppleness, temporary injection reactions are common. You may experience localized stinging, tenderness, redness, swelling, bruising, or temporary spotting. Because the verified formulation does not list lidocaine, the doctor may discuss separate comfort measures prior to treatment. Less common but important risks include infection, allergic reaction, or persistent nodules. If you experience heavy bleeding, fever, foul-smelling discharge, or severe pelvic pain after treatment, you must seek prompt medical care, as these are not routine side effects.
Read about informed consent07 / Recovery
You will receive treatment-specific guidance on what to expect, how to care for the area and when to contact the clinic with a question.
Contact the clinic08 / FAQ
Helpful answers for planning your consultation and understanding the treatment experience.
NEWGyn is an Italian Class III medical device containing highly purified polynucleotides, noncrosslinked HA and mannitol. It is intended for selected adult vulvar and vaginal tissue concerns after medical assessment.
No. NEWGyn and PLINEST are separate Mastelli products within the PN-HPT portfolio. NEWGyn is specifically developed for the vulvovaginal area and has a different formulation and intended purpose.
It contains 10 mg/mL PN-HPT, 10 mg/mL noncrosslinked HA and 220 micromoles/mL mannitol in a single-use 2 mL prefilled syringe.
No estrogen, progesterone or another sex hormone is listed in the formulation. However, being non-hormonal does not mean it is automatically suitable during pregnancy, breastfeeding or cancer treatment.
Yes. Malaysia’s Medical Device Register lists NEWGyn under Ardence Pharma Sdn Bhd with registration number GD9561023-122430, valid from 28 February 2023 to 27 February 2028. Current status should still be checked.
A small uncontrolled study reported improvement in selected vulvar, vaginal and sexual-function measures in postmenopausal women. Results vary, and infection or another medical cause must first be excluded.
Plan your next step
Share your goals with the Eco Botanic team and begin with a personalised consultation.