PB Serum® Medium & High Treatment JB

PB Serum® Medium & High JB – Recombinant Enzyme Therapy

PB Serum Medium & High are injectable medical devices used in our Johor Bahru clinic. They contain a blend of recombinant enzymes, such as lipase, collagenase, and lyase. This therapy may help improve the appearance of cellulite, remodel fibrotic tissue, and support localised fat reduction plans for suitable patients. The doctor selects either Medium or High based on your specific concern, whether it is for fibrous cellulite or stubborn fat pads. Suitability is determined by a medical doctor, and individual results can vary.

At Medi Clinic JB, our doctor provides this treatment for residents of Johor Bahru and many patients who travel from Singapore for professional, doctor-led aesthetic care. Our clinic is conveniently located for those in Taman Pelangi, Mount Austin, and Iskandar Puteri. We focus on a detailed consultation process where our doctor assesses your condition, discusses your goals, and explains the treatment. This approach ensures you have realistic expectations about the outcomes. This commitment to clear communication and safety is why patients from Bukit Indah, Medini, and across the causeway trust our clinic.

While many doctors hold LCP certification in Malaysia, the quality of enzyme-based treatments depends on the doctor’s assessment, correct enzyme selection, and a disciplined treatment protocol. Our focus is on meticulous mapping and aseptic preparation to ensure a structured and safe procedure. We provide clear pricing and structured follow-up visits, which is highly valued by our patients from both JB and Singapore. Our goal is to build long-term trust through consistent care and sensible results.
PB Serum vials prepared for recombinant enzyme therapy at Medi Clinic in Johor Bahru, a trusted option for cellulite and fibrosis treatment for patients from JB and Singapore

How PB Serum Enzymes Work on Fat & Fibrosis

PB Serum therapy works by introducing specific enzymes into areas with cellulite, localised fat, or fibrous tissue. These enzymes are proteins that help to break down certain components in the tissue. This approach is valued by our patients from Taman Molek, Tebrau, and Permas Jaya for its targeted nature.

The process is based on a few key actions:
  • Targeting Fat Cells: The enzyme lipase helps to break down triglycerides, which are fats stored in fat cells. This can support the reduction of small, localised fat deposits that are resistant to diet and exercise.
  • Breaking Down Fibrous Bands: The enzyme collagenase works on disorganised collagen. In cases of cellulite, tight fibrous bands pull the skin down, creating dimples. Collagenase may help to soften these bands, which can lead to a smoother skin appearance.
  • Improving Fluidity: The enzyme lyase (or hyaluronidase) helps to break down molecules that retain excess fluid in the tissue. This can improve tissue drainage and reduce swelling, making the area feel less congested and lumpy.
Over a series of treatments, this enzyme activity may help to smooth cellulite dimples, soften tight or fibrotic areas like certain scars, and refine the contour of treated areas. It is important to remember that these treatments are part of a broader plan, and results can vary between individuals.
A doctor at Medi Clinic JB carefully mapping treatment areas for PB Serum enzyme therapy for a patient seeking cellulite reduction
An illustration of common PB Serum treatment areas like the abdomen, thighs, and jowls, as performed at Medi Clinic Johor Bahru

Choosing the Right Enzyme Blend For You

Our doctor at Medi Clinic JB selects the appropriate PB Serum formulation after a careful assessment. This personalised choice is important for patients from areas like Setia Tropika, Kempas, and Larkin who want a targeted, doctor-managed treatment.

The two main formulations have different primary goals:
  • PB Serum Medium: This formulation has a higher concentration of the enzyme Lipase. Its main focus is on reducing small, localised fat deposits. It is often chosen for areas where stubborn fat pads contribute to contour issues or cellulite. Common areas include the jawline and jowl area, abdomen, thighs, and arms.
  • PB Serum High: This blend has a higher concentration of the enzyme Collagenase. It is designed to target fibrotic or hardened tissue. It is often used to help soften post-liposuction nodules, certain types of scars, and areas with dense, fibrous cellulite where tight bands are the main problem. The doctor selects the treatment areas based on a physical examination.
In your consultation, the doctor will explain which formulation, or combination of treatments, is most suitable for your specific condition. The decision is always based on a medical evaluation to ensure the plan is appropriate and safe for your individual needs.

What to Expect During Your PB Serum Plan

Your PB Serum journey at Medi Clinic JB is a structured process. We ensure patients from Johor and our visitors from Singapore are comfortable and well-informed at every step.

  1. Medical Consultation and Assessment: Your first step is a private consultation with our doctor. The doctor will assess the target area, discuss your concerns, and review your medical history to confirm you are a suitable candidate. We will explain what PB Serum may help with and set clear, realistic expectations.
  2. Treatment Mapping and Preparation: On your treatment day, the doctor will map the precise injection points on the target area. The area will be cleaned, and a topical numbing cream may be applied to enhance comfort. The PB Serum enzymes are then prepared according to strict aseptic techniques.
  3. The Injection Process: The doctor will perform a series of small, targeted injections into the mapped areas. The procedure itself is relatively quick, though this depends on the size and number of areas being treated. Most patients find the process manageable.
  4. Post-Treatment Care: After the injections, you may notice some redness, swelling, tenderness, or bruising in the treated area. These are common effects that usually settle over a few days. We will provide simple aftercare instructions, which may include avoiding heat, strenuous exercise, or massage for a short period.
  5. Follow-Up and Further Sessions: A typical treatment plan involves 3 to 6 sessions, spaced about 2 to 4 weeks apart. Results may become noticeable gradually over the course of the treatment plan. We will schedule review appointments to monitor your progress and determine if further sessions are needed. The doctor will always customise the plan based on your response.
A patient comfortably undergoing a doctor-led PB Serum enzyme therapy session at our welcoming Johor Bahru clinic, popular with Singaporeans.
A diagram illustrating the safety-first approach of PB Serum therapy, showing how enzymes are targeted into subcutaneous tissue in our JB clinic

A Focus on Patient Safety

Patient safety is our main priority at Medi Clinic JB. PB Serum treatments are performed by a medical doctor after a full suitability assessment. While the treatment is generally well-tolerated, it is important to understand the potential side effects and who it is suitable for.

This treatment may not be suitable for everyone. It is important to disclose your full medical history during your consultation. Conditions that may prevent treatment include pregnancy or breastfeeding, active skin infections in the area, or certain uncontrolled medical conditions.

Following the treatment, it is normal to experience some temporary side effects. These are typically mild and resolve on their own:
  • Redness and Swelling: The treated area will likely be red and swollen for a few days. This is a normal inflammatory response.
  • Tenderness: The area may feel tender or sore to the touch for several days.
  • Bruising: Bruising at the injection sites is possible and can take a week or two to fully fade.
This treatment is not a weight-loss programme and is not a replacement for a healthy diet and lifestyle. It is designed to address localised concerns like cellulite and small fat pads. All potential side effects and risks will be discussed in detail during your consent process.

Realistic Outcomes and Clinical Evidence

It is important for our patients from Johor Bahru and Singapore to have clear and realistic expectations about PB Serum treatments. The results can be gradual and will vary from person to person.

  • Clinical Studies: Some studies of enzyme mixtures containing lipase, collagenase, and hyaluronidase have reported improvements in the appearance of cellulite and subcutaneous fat for some patients. However, the evidence is still developing, and larger, longer-term trials are ongoing.
  • Expected Effects: The reported effects are often mild and transient. This treatment is not a “miracle cure” but may support a broader body-contouring plan. We do not promise specific centimetre loss or permanent fat removal.
  • Gradual Improvement: The most noticeable improvements often develop over a full course of 3 to 6 sessions. The body needs time to respond to the enzymes and clear away the broken-down fat and fibrotic tissue. Patience is important.
The longevity of the results depends on factors like your lifestyle, diet, and genetics. Maintaining a stable weight and active lifestyle can help support the outcomes. During your consultation, our doctor will provide an honest assessment of what you might realistically expect based on your individual condition.
A doctor at Medi Clinic discussing a PB Serum treatment plan with a patient, focusing on realistic outcomes and gradual results in Johor Bahru
The welcoming and professional interior of Medi Clinic in Johor Bahru, where patients from Singapore and local areas like Taman Sentosa and Taman Abad receive trusted care for PB Serum treatments

Why Patients from JB and Singapore Trust Medi Clinic

In Johor Bahru, patients have many aesthetic choices, especially in areas like Taman Pelangi. Yet, many residents from Taman Sutera Utama and Seri Alam, along with a growing number of patients from Singapore, choose Medi Clinic JB for their care.

Here is what makes our clinic a trusted choice:
  • Doctor-Led Protocols: The effectiveness of enzyme therapy depends on correct assessment, dosing, and technique. Our doctor personally manages every step, from the initial consultation and mapping to the final review.
  • Transparent and Honest Counselling: We believe in education, not persuasion. We provide clear explanations about the treatment, potential outcomes, and costs. Our goal is to ensure you make a confident and informed decision without pressure.
  • A Focus on Safety and Aseptic Technique: We adhere to strict medical standards for preparing and administering injections. Patient safety is our highest priority, and we maintain a clean and professional environment.
  • Realistic Expectations: We provide honest counselling about what this therapy can and cannot do. We focus on achieving gradual, natural-looking improvements as part of a sensible treatment plan.
  • Cross-Border Friendly Care: We understand the needs of our Singapore patients. We offer flexible scheduling and clear communication to make your visits convenient and stress-free. Our transparent pricing and structured follow-ups are highly valued.

Frequently Asked Questions About PB Serum

Here are answers to common questions about PB Serum Medium & High. For personalised medical advice, please arrange a consultation with our doctor.

What is PB Serum Medium & High?

PB Serum Medium & High are injectable treatments using recombinant enzymes. Medium focuses on reducing localised fat with lipase, while High targets fibrous tissue and scars with collagenase. The doctor chooses the right one for your needs. It is a medical procedure, and results vary.

Who is a good candidate in Johor Bahru?

A good candidate is an adult with concerns like stubborn cellulite dimples, small localised fat pads, or post-liposuction fibrosis. It is for those who are close to their ideal weight and have realistic expectations. A doctor in our JB clinic must perform an assessment to confirm suitability.

How many sessions are needed?

A typical plan involves 3 to 6 sessions. The sessions are usually spaced about 2 to 4 weeks apart. The exact number of treatments depends on your specific condition, the area being treated, and how your body responds. The doctor will create a personalised schedule for you.

What can it help with?

This therapy may help improve the appearance of cellulite, soften fibrous tissue in certain scars, and support fat reduction plans for small, localised areas. It can also be used to address nodules or lumps that can sometimes form after liposuction. The doctor will assess if it is right for your concern.

What is the downtime and side effects?

Common side effects include redness, swelling, tenderness, and bruising in the treated area. These effects are temporary and usually resolve within a few days to a week. Most patients can return to light daily activities quickly, but the doctor may advise avoiding heavy exercise for a short time.

How strong is the clinical evidence?

Clinical evidence for enzyme blends is still developing. Some studies suggest they can improve cellulite and local fat, but reported effects are often mild. More large-scale studies are needed for conclusive data. For this reason, we are careful with claims and always emphasise that individual results vary.

Is this the same as other fat dissolving injections?

No. While both are injectable, they use different active ingredients. Many traditional fat dissolvers use acids like deoxycholic acid. PB Serum uses specific enzymes like lipase, collagenase, and lyase. This allows it to target not just fat, but also the fibrous components of cellulite and scars. Our doctor will explain which approach is suitable for you.

Can I combine it with other treatments?

Yes, PB Serum can be part of a larger treatment plan. For example, it can be combined with treatments like microneedling to improve skin texture, or fillers like Belotero to address volume loss in other areas. The doctor will advise on a safe and effective treatment schedule if you are considering multiple procedures.

Is the treatment comfortable?

Comfort levels vary. The treatment involves a series of small injections. We typically apply a topical numbing cream to the area beforehand to make the process more comfortable. Most patients find the procedure tolerable. The doctor will ensure you are as comfortable as possible during the session.

PB Serum Gallery

PB Serum Medium cellulite treatment in Johor Bahru – recombinant enzyme therapy at Medi Clinic
PB Serum High enzyme injections softening fibrosis in JB at Medi Clinic for a patient from Singapore
Doctor mapping PB Serum treatment areas for cellulite and fibrosis in Johor Bahru
PB Serum vials prepared for localised fat and scar treatment at Medi Clinic JB for cross-border patients

Learn more about Recombinant Enzyme Therapy

Download our detailed guide to understand more about how PB Serum’s enzymes may help improve cellulite, fibrosis, and localised fat.
Download Treatment Guide
Medi Clinic JB – PB Serum Smart Guide

PB Serum – Smart Guide

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About PB Serum Therapy

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Why Patients Choose PB Serum Therapy

Patients from Johor Bahru and Singapore consider PB Serum therapy for several reasons. Our doctor will discuss which benefits might apply to you after a full assessment. Results and individual experiences can vary.
Smoothes Cellulite
May help improve the appearance of cellulite dimples.
Refines Contour
Can refine local contours in small, stubborn fat pads.
Softens Fibrosis
Helps to soften tight fibrotic bands and certain types of scars.
Doctor-Led Plan
Treatment areas and dosing are planned and managed by a doctor.
PB Serum Enzyme Therapy vs. Traditional Fat Dissolving Injections
Key Aspect Traditional Fat Dissolving (e.g., Deoxycholic Acid) PB Serum Enzyme Therapy at Medi Clinic JB MULTI-ACTION
Primary Active Ingredient Typically uses a synthetic acid (like deoxycholic acid) to destroy fat cell membranes. Uses a blend of recombinant enzymes (lipase, collagenase, lyase) to target different tissue components.
Mechanism of Action Causes direct destruction of fat cells (adipocytolysis), leading to an inflammatory response to clear the cellular debris. Lipase helps break down fat, while collagenase softens fibrous bands in cellulite and scars. It is a remodelling process, not just fat cell destruction.
Main Target Primarily targets subcutaneous fat. Less effective on the fibrous components of cellulite or scars. Can target both localised fat (Medium formula) and fibrotic tissue (High formula), making it suitable for complex issues like fibrous cellulite.
Common Side Effects Significant swelling, tenderness, numbness, and potential for temporary hardness are very common. Swelling, tenderness, and bruising are also common, but the inflammatory response may differ. Doctor will advise.
Treatment Goal Focused on reducing the number of fat cells in a specific, localised area (e.g., under the chin). Aims to remodel tissue, improve skin appearance, and support fat reduction as part of a broader body contouring plan.
Suitability Best for distinct, small pockets of fat in patients with good skin elasticity. Suitable for a wider range of concerns, including cellulite with dimpling, post-lipo fibrosis, and certain scars, in addition to localised fat.
Doctor Assessment Doctor must assess fat pad location and rule out skin laxity as the primary cause. Doctor assesses fat, fibrosis, and fluid retention to select the correct enzyme formulation (Medium or High) for a targeted approach.
Mechanism of Action
Traditional Fat Dissolving:
Causes direct destruction of fat cells (adipocytolysis), leading to an inflammatory response to clear the cellular debris.
PB Serum Enzyme Therapy at Medi Clinic JB:
Lipase helps break down fat, while collagenase softens fibrous bands in cellulite and scars. It is a remodelling process, not just fat cell destruction.
Main Target
Traditional Fat Dissolving:
Primarily targets subcutaneous fat. Less effective on the fibrous components of cellulite or scars.
PB Serum Enzyme Therapy at Medi Clinic JB:
Can target both localised fat (Medium formula) and fibrotic tissue (High formula), making it suitable for complex issues like fibrous cellulite.
Suitability
Traditional Fat Dissolving:
Best for distinct, small pockets of fat in patients with good skin elasticity.
PB Serum Enzyme Therapy at Medi Clinic JB:
Suitable for a wider range of concerns, including cellulite with dimpling, post-lipo fibrosis, and certain scars, in addition to localised fat.

Arrange Your PB Serum Assessment


The first step is a medical consultation with our doctor to see if PB Serum is right for you. We invite you to schedule an appointment at our Johor Bahru clinic, where we care for patients from local areas like Taman Gaya and Adda Heights, as well as many who travel from Singapore. During your visit, our doctor will perform a detailed assessment, discuss your concerns, and create a personalised plan. We provide clear information so you can make an informed choice. Please book in advance to secure your preferred time.

Trusted doctor at Medi Clinic Johor Bahru, providing PB Serum enzyme treatments for Singaporean and local patients.