Doctor-Led, Product-Specific Care
REJURAN® Polynucleotide Skin Treatment in Johor Bahru
REJURAN is a family of injectable sodium-polynucleotide medical devices used within the skin for selected temporary skin-quality and wrinkle-related improvements. The exact REJURAN product, treatment area, and Malaysian registration must be confirmed before treatment because REJURAN, REJURAN I, REJURAN S, and REJURAN HB plus are not interchangeable.
At Medi Clinic, we believe you should confirm the exact REJURAN product before treating it as a generic skin booster. Treatment involves multiple intradermal injections, and temporary raised injection points (papules) are expected. Changes are gradual, benefits may be subtle, and several sessions may be discussed. We provide a transparent, doctor-led assessment for patients from Johor Bahru, Taman Molek, Iskandar Puteri, and Singapore. We ensure you understand the exact product used rather than relying on marketing claims or guaranteed regeneration promises. No improvement is possible, and no injection is always a valid option.
At Medi Clinic, we believe you should confirm the exact REJURAN product before treating it as a generic skin booster. Treatment involves multiple intradermal injections, and temporary raised injection points (papules) are expected. Changes are gradual, benefits may be subtle, and several sessions may be discussed. We provide a transparent, doctor-led assessment for patients from Johor Bahru, Taman Molek, Iskandar Puteri, and Singapore. We ensure you understand the exact product used rather than relying on marketing claims or guaranteed regeneration promises. No improvement is possible, and no injection is always a valid option.
Understanding Polynucleotides
What is REJURAN?
REJURAN contains purified sodium polynucleotides of salmon origin. It is an intradermal medical device restricted to physician use under current Malaysian records. Polynucleotides (PN) are chains made from nucleotide components, designed to form an injectable gel. Treatment is placed within the dermis to target fine lines, skin texture, and elasticity-related appearance. It does not contain living cells, it is not a stem-cell therapy, and it does not rewrite your DNA.
Crucially, PN and PDRN (polydeoxyribonucleotide) should not be treated as interchangeable labels. They may have different molecular characteristics, manufacturing processes, and regulatory categories. Do not select a treatment based only on the words “salmon DNA” or “PDRN”. Furthermore, REJURAN is not a structural dermal filler, botulinum toxin, exosome, or PRP treatment. It cannot reliably build a chin, remove deep tear troughs, or replace surgical lifting. Our Rejuran skin booster treatment in Johor Bahru focuses on verified, product-specific care.
Crucially, PN and PDRN (polydeoxyribonucleotide) should not be treated as interchangeable labels. They may have different molecular characteristics, manufacturing processes, and regulatory categories. Do not select a treatment based only on the words “salmon DNA” or “PDRN”. Furthermore, REJURAN is not a structural dermal filler, botulinum toxin, exosome, or PRP treatment. It cannot reliably build a chin, remove deep tear troughs, or replace surgical lifting. Our Rejuran skin booster treatment in Johor Bahru focuses on verified, product-specific care.
The REJURAN Product Family
Selecting the Exact Product
REJURAN is not one identical syringe. Different products may differ in sodium-polynucleotide concentration, viscosity, intended skin area, and Malaysian registration.
REJURAN, I, and S: The standard REJURAN is often discussed for general facial skin quality. REJURAN I is commonly associated internationally with thinner periocular (under-eye) skin, while REJURAN S may be considered for selected superficial scar appearance. However, the exact local intended use must always be verified.
REJURAN HB plus: This is a separately registered product containing sodium polynucleotide, sodium hyaluronate (HA), and lidocaine. Its current Malaysian intended purpose is specifically limited to the temporary improvement of adult crow’s feet. Lidocaine may reduce discomfort, but it does not make treatment completely painless. HB plus should not be automatically marketed as a whole-face hydration booster without proper verification.
REJURAN, I, and S: The standard REJURAN is often discussed for general facial skin quality. REJURAN I is commonly associated internationally with thinner periocular (under-eye) skin, while REJURAN S may be considered for selected superficial scar appearance. However, the exact local intended use must always be verified.
REJURAN HB plus: This is a separately registered product containing sodium polynucleotide, sodium hyaluronate (HA), and lidocaine. Its current Malaysian intended purpose is specifically limited to the temporary improvement of adult crow’s feet. Lidocaine may reduce discomfort, but it does not make treatment completely painless. HB plus should not be automatically marketed as a whole-face hydration booster without proper verification.
Managing Skin Recovery
Understanding Papules & Side Effects
Because REJURAN treatment in JB is injected directly into the dermis, small raised injection points (papules) will appear immediately after treatment. These reflect the deposited product and usually settle gradually over a few days, though some may remain longer, especially around the delicate eye area. Papules are expected and are not proof of treatment success.
Common temporary side effects include injection pain, stinging, redness, swelling, tenderness, bruising, itching, and pinpoint bleeding. Serious but unusual risks include infection, allergic reactions, persistent nodules, or vascular injury. Treatment is prohibited for children, adolescents, pregnant women, and lactating women according to current local family registration. If you experience severe symptoms like rapidly increasing swelling, unusual severe pain, or visual changes, urgent medical assessment is required.
Common temporary side effects include injection pain, stinging, redness, swelling, tenderness, bruising, itching, and pinpoint bleeding. Serious but unusual risks include infection, allergic reactions, persistent nodules, or vascular injury. Treatment is prohibited for children, adolescents, pregnant women, and lactating women according to current local family registration. If you experience severe symptoms like rapidly increasing swelling, unusual severe pain, or visual changes, urgent medical assessment is required.
Planning Your Consultation
Doctor-Led Assessment & Safety
A responsible consultation identifies your main concern whether it is fine lines, texture, or scars and confirms if an injectable PN product is medically appropriate. We will review your medical history, allergies, active acne, dermatitis, and any previous fillers or laser procedures. We strictly verify sealed original packaging, exact product names, batch numbers, and Medical Device Authority (MDA) registration before proceeding.
For Singapore Patients: Patients travelling from Singapore for a polynucleotide injection in Johor Bahru should allow time for a proper in-person assessment. Avoid booking from photographs alone. Disclose all previous treatments, consider the visibility of papules and bruising before social events, and ensure you have a plan for follow-up care and urgent cross-border assessment if severe symptoms occur. We prioritise medical oversight over price alone.
For Singapore Patients: Patients travelling from Singapore for a polynucleotide injection in Johor Bahru should allow time for a proper in-person assessment. Avoid booking from photographs alone. Disclose all previous treatments, consider the visibility of papules and bruising before social events, and ensure you have a plan for follow-up care and urgent cross-border assessment if severe symptoms occur. We prioritise medical oversight over price alone.
Frequently Asked Questions About REJURAN Treatment in JB
Here are answers to common questions about REJURAN, PN skin boosters, and polynucleotide skin treatments. This information helps you have an informed discussion with our doctor.
What is REJURAN?
REJURAN is a family of injectable sodium-polynucleotide medical devices used within the dermis for selected temporary skin-quality and wrinkle-related improvements.
Is REJURAN the same as PDRN?
No. Current Malaysian REJURAN records identify sodium polynucleotides. PN and PDRN should not be used as automatic synonyms.
Is every REJURAN product the same?
No. REJURAN, REJURAN I, REJURAN S and REJURAN HB plus have different formulations, intended uses and registration details.
What is REJURAN HB plus?
It is a separate product containing sodium polynucleotide, sodium hyaluronate and lidocaine. Its current Malaysian intended purpose specifically concerns temporary improvement of adult crow’s feet.
Is REJURAN a dermal filler?
No. It is not intended to provide the same structural volume or facial contour change as dermal filler.
Can REJURAN remove eye bags or deep tear troughs?
No. It may be considered for selected fine-line or skin-quality concerns but cannot remove orbital fat or replace structural volume reliably.
What are the common side effects?
Possible effects include injection pain, redness, swelling, bruising, pinpoint bleeding, tenderness and temporary raised papules.
How many REJURAN sessions are needed?
There is no universal course. The plan depends on the exact product, registered purpose, treatment area, response and patient preference.
Can REJURAN be used during pregnancy or breastfeeding?
No. The current Malaysian REJURAN family registration prohibits use during pregnancy and lactation.
PN Identity, Product Family, Intradermal Recovery & MDA Verification
REJURAN Is a Product Family — Not a Generic “Salmon DNA Skin Booster”
REJURAN products contain purified sodium polynucleotides of salmon origin and are used within the dermis for selected temporary skin-quality and wrinkle-related improvements. REJURAN, REJURAN I, REJURAN S and REJURAN HB plus are not interchangeable. A responsible plan confirms the exact concern, product, local intended use, Malaysian registration, sealed packaging and batch before treatment.
REJURAN product guide
Select a product-planning pathway
Then review four checkpoints: PN identity and category differences; REJURAN family selection; papules, reactions and urgent red flags; and MDA registration, sealed packaging, batch traceability, contraindications and cross-border follow-up.
Treatment Timeline
Find Out if REJURAN is for You
Our doctor at Medi Clinic Johor Bahru can accurately assess your skin condition to determine if an injectable PN product is medically appropriate. We will explain realistic expectations, side effects like papules, and ensure safety remains the top priority. Try our brief quiz below to check your understanding.
How Well Do You Understand REJURAN Polynucleotide Treatment?
Understand PN Safety in 60 seconds
REJURAN Treatment Suitability Quiz
Step 1 / 8
This quiz cannot confirm REJURAN suitability. A doctor must assess the skin concern, treatment area, medical history, allergies, previous procedures, exact product, Malaysian registration, expected papules, risks and alternatives.
💬 Book REJURAN Consultation
Timeline & Realistic Expectations
Understanding the Treatment Timeline
At Medi Clinic, we believe in clear communication. Medical skin-quality treatment is a process, not a quick fix. We help patients from Johor Bahru and Singapore set realistic goals and monitor health improvements safely over time without promising dramatic or permanent transformations.
Assessment
Comprehensive medical history, exact product selection, and MDA registration check.
Papules
Multiple intradermal injections; expect temporary raised papules, redness, and swelling.
Gradual Changes
Visible skin-quality changes develop gradually over several weeks as the skin responds.
Maintenance
Optional follow-up to review benefits, side effects, and determine if further sessions are appropriate.
Compare Skin-Quality Options
| Treatment Option | Main Limitation | Main Purpose MEDICAL |
|---|---|---|
| REJURAN PN | Does not provide major structural volume; evidence and indications are product-specific. | Selected temporary skin-quality, wrinkle or tissue-restoration appearance. |
| REJURAN HB PLUS | Should not be marketed automatically for every face or body area. | Current Malaysian purpose specifically concerns temporary improvement of adult crow’s feet. |
| HA SKIN BOOSTER | Different product category, swelling behaviour and registration. | Selected hydration, smoothness or skin-quality goals. |
| DERMAL FILLER | Different vascular-risk profile and cannot be replaced by PN treatment. | Temporary volume and contour. |
| BOTULINUM TOXIN | Does not improve skin volume or hydration directly. | Temporary reduction of selected muscle activity. |
| PRP | Preparation varies and it is not a PN product. | Selected skin-quality or tissue-related treatment. |
| NO PROCEDURE | The visible concern remains, but injection-related risk is avoided. | Skincare, monitoring or acceptance. |
REJURAN PN
Main Limitation:
Does not provide major structural volume; evidence and indications are product-specific.
Main Purpose:
Selected temporary skin-quality, wrinkle or tissue-restoration appearance.
REJURAN HB PLUS
Main Limitation:
Should not be marketed automatically for every face or body area.
Main Purpose:
Current Malaysian purpose specifically concerns temporary improvement of adult crow’s feet.
HA SKIN BOOSTER
Main Limitation:
Different product category, swelling behaviour and registration.
Main Purpose:
Selected hydration, smoothness or skin-quality goals.
DERMAL FILLER
Main Limitation:
Different vascular-risk profile and cannot be replaced by PN treatment.
Main Purpose:
Temporary volume and contour.
BOTULINUM TOXIN
Main Limitation:
Does not improve skin volume or hydration directly.
Main Purpose:
Temporary reduction of selected muscle activity.
PRP
Main Limitation:
Preparation varies and it is not a PN product.
Main Purpose:
Selected skin-quality or tissue-related treatment.
NO PROCEDURE
Main Limitation:
The visible concern remains, but injection-related risk is avoided.
Main Purpose:
Skincare, monitoring or acceptance.
Book Your Skin Assessment
Discuss Your Skin Goals with Our Doctor
Book a doctor-led REJURAN consultation at Medi Clinic in Johor Bahru to assess your skin concern and confirm which Malaysian-registered REJURAN product, if any, is appropriate for the proposed treatment area. We will explain realistic benefits, limitations, expected papules, common side effects, and verify product authenticity before any procedure. Whether you are a local resident or visiting from Singapore, we prioritise medical safety and respect the no-treatment option.
Explore our other aesthetic services.
30+
Years of experience
4K+
Happy customers
15K+
Success Story
70+
Services Provided
